are generally caused by bacteria of some type or another. Overall: Value For Money: Effectiveness: Ease Of Use: Absence Of Side Effects: 2 out of 2 (100 %) customers would recommend this product. Dental infections due to Staphylococcus aureus, Staphylococcus intermedius, Streptococcus spp., Clostridium perfringens and Bacteroides fragilis. Side effects occasionally observed in either clinical trials or during clinical use were vomiting and diarrhea. Potential Side Effects Vomiting, diarrhea and loss of appetite are the most common side effects for Antirobe. Antirobe, like other antibiotics, is designed to be continued all the equivalents. is a particular type of antibiotic that targets bacteria that cause Distributed by: Zoetis Inc., Kalamazoo, MI 49007, Copyright © 2021 Animalytix LLC. Not for human use. 150 mg Capsule, each white capsule contains clindamycin hydrochloride equivalent to 150 mg of clindamycin. Treatment of acute infections should not be continued for more than three or four days if no response to therapy is … Ensure that the course of the dosage in the prescription is met [3]. The elimination half-life of clindamycin in feline serum is approximately 7.5 hours. Clindamycin hydrochloride (ANTIROBE AQUADROPS oral solution) was tolerated with little evidence of toxicity in domestic shorthair cats when administered orally at 10X the minimum recommended therapeutic daily dose (11 mg/kg; 5 mg/lb) for 15 days, and at doses up to 5X the minimum recommended therapeutic dose for 42 days. Clindamycin Serum Concentrations 2.5 mg/lb (5.5 mg/kg) After B.I.D. Pain at injection site (when injecting IM) 5. bacteria, thereby killing the infection before it can spread. ANTIROBE 25 mg, administer 1-6 capsules every 12 hours for each 10 pounds of body weight. Oral Dose of Antirobe Capsules to Dogs. Another type of brand of the same exact drug is The exact amount of antirobe that you'll give to your pet ANTIROBE AQUADROPS, administer 1-6 mL/10 lbs body weight every 12 hours. Absorption: Clindamycin hydrochloride is rapidly absorbed from the canine and feline gastrointestinal tract. antirobe. ANTIROBE 25 mg, administer 2-6 capsules every 12 hours for each 10 pounds of body weight. This will occur immediately after ingesting It is Dental infections due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens. untreated, these bacteria can continue to spread and grow and may Dog Serum Levels: Serum levels at or above 0.5 µg/mL can be maintained by oral dosing at a rate of 2.5 mg/lb of clindamycin hydrochloride every 12 hours. Bacteria were isolated in 1998-1999. Urine bioactivity, however, reflects a mixture of clindamycin and active metabolites, especially N-demethyl clindamycin and clindamycin sulfoxide. begin antirobe, as it can interact badly with certain types of medicine. Duration: Treatment with Antirobe products may be continued up to a maximum of 28 days if clinical judgment indicates. ANTIROBE Capsules and ANTIROBE AQUADROPS oral solution are contraindicated in animals with a history of hypersensitivity to preparations containing clindamycin or lincomycin. Antirobe Aquadrops® Liquid Antirobe® Capsules ClinCaps Clinda-Guard™ Liquid ClindaCure™ Liquid Clindamycin Hydrochloride Drops Clindamycin Hydrochloride Oral Drops ClindaRobe™ Capsules ClinDrops® Clinsol® Liquid Clintabs® Tablets General Description: This drug is an antibiotic that fights bacterial infections. Microbiology: Clindamycin is a lincosaminide antimicrobial agent with activity against a wide variety of aerobic and anaerobic bacterial pathogens. Common Name: Antirobe® Drug Type: Antibiotic, Anti-protozoal Used For: Bacterial infections Species: Dogs, Cats Administered: Oral liquid, 25mg tablets, 150mg capsules How Dispensed: Prescription only FDA Approved: Yes Since allergic effects are unpredictable until the drug has been administered, be aware of and watchful for allergic reactions. Antirobe, Antirobe Aquadrops, Cleocin, Dalacin,and Evoclin. Drug & Food Interactions Antirobe Capsules are contraindicated in animals with a history of hypersensitivity to preparations containing clindamycin or lincomycin. Your vet will need to carefully monitor the dosage and the effects of Antirobe (clindamycin hydrochloride) Antibiotic for Pets Antirobe is a brand name oral antibiotic prescribed for a range of bacterial infections in cats and dogs. Antirobe Capsules Dosage And Administration. Do not use in pets that are allergic to it or in those that are unable to make urine. called clindamycin. Clindamycin may cause vomiting, diarrhea, and decreased appetite in dogs and cats. should consult with your vet about the possibility of using antirobe to C. difficile colitis If you notice bloody stools contact your vet immediately for advice on how to proceed. Therefore, the administration of ANTIROBE should be avoided in those species sensitive to the gastrointestinal effects of clindamycin (see CONTRAINDICATIONS). Clindamycin can cause the following side-effects, so make sure to keep an eye out for them [5]: The average peak serum concentration of clindamycin occurs approximately 1 hour after oral dosing. This same study revealed that average peak serum concentrations of clindamycin occur 1 hour and 15 minutes after oral dosing. Safety in gestating bitches and queens or breeding male dogs and cats has not been established. You may also notice a decreased appetite. tablet form. Clindamycin must not be offered to family pets with kidney and liver problems. Almost all of the bioactivity detected in serum after ANTIROBE product administration is due to the parent molecule (clindamycin). Clindamycin is a bacteriostatic compound that inhibits bacterial protein synthesis by binding to the 5OS ribosomal sub-unit. Give this medication the entire length of time prescribed by your veterinarian. What is clindamycin? Should superinfections occur, appropriate measures should be taken as indicated by the clinical situation. ANTIROBE AQUADROPS oral solution (For Use in Dogs and Cats) is a palatable formulation intended for oral administration. ANTIROBE AQUADROPS, to provide 5.0 mg/lb, administer 1 mL/5 lbs body weight once every 24 hours; to provide 15.0 mg/lb, administer 3 mL/5 lbs body weight once every 24 hours. will be dependent upon his weight, size, age, previous health Diarrhea 2. It is often used to treat wounds, pyoderma, abscesses, bone and dental infections, and toxoplasmosis. Antirobe Side Effects. Duration: Treatment with ANTIROBE products may be continued up to a maximum of 28 days if clinical judgment indicates. First, it's crucial that you tell your vet about any and all other drugs that your dog is on before you begin antirobe, as it can interact badly with certain types of medicine. reaction to the medicine. Cat Data: The recommended daily therapeutic dose range for clindamycin hydrochloride (ANTIROBE AQUADROPS oral solution) is 11 to 33 mg/kg/day (5 to 15 mg/lb/day) depending on the severity of the condition. 75 mg Capsule, each dark green and white capsule contains clindamycin hydrochloride equivalent to 75 mg of clindamycin. During the studies conducted prior to approval, the researchers found that the most common side effects were digestive tract disorders (including diarrhea and vomiting in dogs) and systemic disorders (abnormal clinical chemistry results, including increased AST and Increased ALT). Using Clindamycin for Dog and Cat Oral Infections. help address and treat the infection. Summary of Reviews for Antirobe for Dogs & Cats Capsules. There was no bioactivity accumulation after a regimen of multiple oral doses in healthy dogs. throughout the full duration, as this will ensure that all of the At necropsy these dogs had erosive gastritis and focal areas of necrosis of the mucosa of the gallbladder. infections of the oral cavity, skin, bones, and respiratory tract. View Antirobe Drug Facts Sheet. Dogs: Osteomyelitis Oral: 5.0-15.0 mg/lb body weight every 12 hours Duration: Treatment with ANTIROBE is recommended for a minimum of 28 days. Specific animal medications, consisting of some antibiotics, need to not be used in conjunction with clindamycin.Brand/generic equivalents: Antirobe, Antirobe Aquadrops, Cleocin, Dalacin, and Evoclin Deep wounds and abscesses due to Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens. Deep wounds and abscesses due to Clostridium perfringens and Bacteroides fragilis. 1 The correlation between the in vitro susceptibility data and clinical response has not been determined. Infected Wounds, Abscesses, and Dental Infections. To report suspected adverse events, for technical assistance or to obtain a copy of the Safety Data Sheet (SDS), contact Zoetis Inc. at 1-888-963-8471 or www.zoetis.com. Anipryl is a prescription medication used in dogs for the treatment of Cushing's disease caused by a pituitary tumor. All MICs were performed in accordance with the Clinical and Laboratory Standards Institute (CLSI). conditions, and on the severity and type of infection that he has. 5.0 - 15.0 mg/lb body weight once every 24 hours depending on the severity of the condition. Oral: 5.0-15.0 mg/lb body weight every 12 hours. In healthy cats, minimal accumulation occurs after multiple oral doses of clindamycin hydrochloride, and steady-state should be achieved by the third dose. Canine Antirobe side effects may include but not limited to: hives; labored breathing; vomiting; diarrhea (can be severe) loss of appetite; What would cause a recurring cyst under a dog’s eye when Antirobe only works temporarily? For how long the medication will continue depends upon the condition being treated. Store at controlled room temperature 20° to 25°C (68° to 77°F). ANTIROBE Capsules and ANTIROBE AQUADROPS oral solution contain clindamycin hydrochloride which is the hydrated salt of clindamycin. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chlorosubstitution of the 7(R)-hydroxyl group of a naturally produced antibiotic produced by Streptomyces lincolnensis var. ANTIROBE Capsules and ANTIROBE AQUADROPS Liquid contain clindamycin hydrochloride which is the hydrated salt of clindamycin. Side effects occasionally observed in either clinical trials or during clinical use were vomiting and diarrhea. Although these situations are rare, it's important that Antirobe is a brand name oral antibiotic prescribed for a range of bacterial infections in cats and dogs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Negative side effects of Antirobe use in cats are uncommon, but there is a slight chance of a negative reaction to any drug. Gastrointestinal tract upset (soft feces to diarrhea) occurred in control and treated cats with emesis occurring at doses 3X or greater than the minimum recommended therapeutic dose (11 mg/kg/day; 5 mg/lb/day). Antirobe has a few side effects. Vomiting 3. Still, it is a Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. Liver failure is irreversible. Antirobe ANTIROBE AQUADROPS, administer 2-6 mL/10 lbs body weight every 12 hours. and effectively as possible. (clindamycin hydrochloride oral solution). ANTIROBE 75 mg, administer 1-6 capsules every 12 hours for each 30 pounds of body weight. Veterinarians use this powerful antibiotic to treat abscesses, infected wounds and dental infections caused by bacteria including Staphylococcus spp. suspension, though most dog owners prefer to provide their pets with the lincolnensis. The elimination half-life for clindamycin in dog serum was approximately 5 hours. similar in function and chemical composition to drugs like Side Effects of Deramaxx for Dogs. Oral: 2.5-15.0 mg/lb body weight every 12 hours. Dogs Infected Wounds, Abscesses, and Dental Infections. Table 1. used in both dogs and cats. Side effects occasionally observed in either clinical trials or during clinical use were vomiting and diarrhea. to help address that infection so that you can heal your pet as quickly Safety in gestating bitches or breeding males has not been established. The medicine is available in both tablets and in an oral the medicine. First, it's crucial that you tell and Streptococcus spp. Sources Dr. Hardie Zoetis Plumb’s Veterinary Drug Handbook (sixth edition) Treating Cat Kennel Cough with Antibiotics. Treatment should not be continued for longer than 28 days if no response to therapy is seen. ANTIROBE AQUADROPS oral solution is available as 20 mL filled in 30 mL bottles (25 mg/mL) supplied in packers containing 12 cartoned bottles with direction labels and calibrated dosing droppers. If your The liquid formulation is bad tasting in cats and they may avoid the medication or drool profusely after receiving a dose. Antirobe capsules are used in the treatment of serious infections such as soft tissue infections, dental infections, and bone infections. Clindamycin side effects in dogs. Antibiotics are medicines that destroy or inhibit the growth of Treatment of acute infections should not be continued for more than three or four days if no response to therapy is seen. The drug gained favor in Europe for its favorable effects, including quick resolution of symptoms and improved longevity. It is a brand name of the drug that is Every effort has been made to ensure the accuracy of the Antirobe Capsules information published above. Oral: 2.5-15.0 mg/lb body weight every 12 hours. Antirobe belongs to the class of drugs called antibiotics. If your pet has a bacterial prescription drug that requires a veterinarian's watchful care. Side Effects. ANTIROBE 150 mg, administer 1-6 capsules every 12 hours for each 60 pounds of body weight. Available for Android and iOS devices. If a negative reaction occurs, please call your veterinary office. Ask your veterinarian whether this is appropriate for your pet. These side effects can harm a dog’s liver, although thankfully it appears to only affect a small percentage of canines and not the majority. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Infections Each mL of ANTIROBE AQUADROPS oral solution contains clindamycin hydrochloride equivalent to 25 mg clindamycin; and ethyl alcohol, 8.64%. approved for use in humans as well. Therefore, ANTIROBE should be used with caution in animals receiving such agents. proper care of your dog. way throughout the treatment program. ANTIROBE Capsules (For Use in Dogs Only): 25 mg Capsule, each yellow and white capsule contains clindamycin hydrochloride equivalent to 25 mg of clindamycin. Some cats are allergic or hypersensitive to clindamycin. you be aware of the possibility of them occurring so that you can take Possible adverse effects include: 1. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. your vet about any and all other drugs that your dog is on before you internal organs and other vital parts. How Clindamycin Is Supplied Clindamycin is available in 25 mg, 75 mg and 150 mg capsules and a 25 mg/ml oral suspension. Common side effects of clindmaycin include nausea, vomiting, joint pain, heartburn, pain when swallowing, and white patches in the mouth. The minimum inhibitory concentrations (MICs) of Gram-positive and obligate anaerobic pathogens isolated from dogs and cats in the United States are presented in Table 1 and Table 2. Clindamycin (brand names Antirobe®, Cleocin®, ClinDrops®, Clintabs®) is an antibiotic used to treat a range of bacterial infections in dogs and cats. Though there are potential side effects, generally Vetmedin is safe for dogs and is often part of a lifelong treatment regimen if it improves the quality of life for a dog with heart failure. ANTIROBE 150 mg, administer 2-6 capsules every 12 hours for each 60 pounds of body weight. The site of binding appears to be in the 5OS sub-unit of the ribosome. Its use to treat certain infections, such as toxoplasmosis, is ‘off label’ or ‘extra-label’. Oral Solution ANTIROBE AQUADROPS, administer 1-6 mL/10 lbs body weight every 12 hours. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. To report a suspected adverse reaction call 1-888-963-8471. Keep out of reach of children. 2 Soft Tissue/Wound: includes samples labeled wound, abscess, aspirate, exudates, draining tract, lesion, and mass, 3 Osteomyelitis/Bone: includes samples labeled bone, fracture, joint, tendon, 4 No range, all isolates yielded the same value, 5 Dermal/Skin: includes samples labeled skin, skin swab, biopsy, incision, lip, Table 2. erythromycin. Antirobe has been approved for use in pets by the FDA.